Celosti

Celosti may be available in the countries listed below.

Ingredient matches for Celosti

Celecoxib

Celecoxib is reported as an ingredient of Celosti in the following countries:

• Vietnam

International Drug Name Search

ipratropium Inhalation, oral/nebulization

ip-ra-TROE-pee-um BROE-mide

Commonly used brand name(s)

In the U.S.

• Atrovent

In Canada

• Alti-Ipratropium


• Alti-Ipratropium With Preservative


• Apo-Ipravent


• Ipratropium Bromide Nebuamp


• Ipratrovent Sterules


• Ratio-Ipratropium


• Ratio-Ipratropium Udv

Available Dosage Forms:

• Solution


• Aerosol Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Ipratropium

Uses For ipratropium

Ipratropium is used to help control the symptoms of lung diseases, such as asthma, chronic bronchitis, and emphysema. It is also used to treat air flow blockage and prevent the worsening of chronic obstructive pulmonary disease (COPD).

Ipratropium belongs to the family of medicines known as bronchodilators. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs.

ipratropium is available only with your doctor's prescription.

Before Using ipratropium

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ipratropium, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ipratropium or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ipratropium in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ipratropium in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ipratropium, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ipratropium with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Betel Nut

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of ipratropium. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to atropine, scopolamine, or hyoscyamine—Should not be used in patients with this condition.

• Difficult urination or


• Enlarged prostate or


• Narrow-angle glaucoma or


• Urinary bladder blockage—Use with caution. May make these conditions worse.

Proper Use of ipratropium

ipratropium usually comes with patient instructions. Read them carefully before using the medicine. If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor to show you how to use it.

Use ipratropium only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using ipratropium without telling your doctor. To do so may cause your lung condition to become worse.

Keep the spray or solution away from the eyes. ipratropium may cause eye pain or discomfort, irritation, blurred vision, or start seeing halos or odd colors when you look at things. Closing your eyes while you are inhaling ipratropium may keep the medicine from getting into your eyes. If it does come into contact with your eyes, check with your doctor right away.

If you are taking ipratropium every day to help control your symptoms, it must be taken at regularly spaced times as ordered by your doctor.

For patients using ipratropium inhalation aerosol:

• If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor to show you how to use it. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.


• There are two formulas of the inhaled aerosol. One contains chlorofluorocarbons and the other contains HFA as the propellant. The taste and inhalation of these may seem different, but the safety and effectiveness of both formulas are similar.


• The ipratropium aerosol canister provides about 200 inhalations, depending on the size of the canister your doctor ordered. You should try to keep a record of the number of inhalations you use so you will know when the canister is almost empty. This canister, unlike some other aerosol canisters, cannot be floated in water to test its fullness.


• When you use the inhaler for the first time, or if you have not used it for a while, the inhaler may not give the right amount of medicine with the first puff. Therefore, before using the inhaler, test or prime it.


• To test or prime the inhaler:
  
  • Insert the canister firmly into the clean mouthpiece according to the manufacturer's instructions. Check to make sure it is placed properly into the mouthpiece.
  
  
  • Take the cap off the mouthpiece and shake the inhaler three or four times.
  
  
  • Hold the inhaler away from you at arm's length and press the top of the canister, spraying the medicine two times into the air. The inhaler will now be ready to give the right amount of medicine when you use it.
  
  
  • If the inhaler is not used for more than 3 days, prime the inhaler two times to prepare it for use.
  
  


• To use the inhaler:
  
  • Using your thumb and one or two fingers, hold the inhaler upright, with the mouthpiece end down and pointing toward you.
  
  
  • Take the cap off the mouthpiece. Check the mouthpiece to make sure it is clear. Then, gently shake the inhaler three or four times.
  
  
  • Breathe out slowly to the end of a normal breath.
  
  
  • Use the inhalation method recommended by your doctor:
    
    • Open-mouth method—Place the mouthpiece about 1 or 2 inches (2 finger-widths) in front of your widely opened mouth. Make sure the inhaler is aimed into your mouth so the spray does not hit the roof of your mouth or your tongue.
    
    
    • Closed-mouth method—Place the mouthpiece in your mouth between your teeth and over your tongue with your lips closed tightly around it. Make sure your tongue or teeth are not blocking the opening.
    
    
  
  
  • Start to breathe in slowly and deeply through your mouth. At the same time, press the top of the canister once to get one puff of medicine. Continue to breathe in slowly for 5 to 10 seconds. Count the seconds while breathing in. It is important to press the canister and breathe in slowly at the same time so the medicine gets into your lungs. This step may be difficult at first. If you are using the closed-mouth method and you see a fine mist coming from your mouth or nose, the inhaler is not being used correctly.
  
  
  • Hold your breath as long as you can up to 10 seconds. This gives the medicine time to settle into your airways and lungs.
  
  
  • Take the mouthpiece away from your mouth and breathe out slowly.
  
  
  • If your doctor has told you to inhale more than one puff of medicine at each dose, gently shake the inhaler again, and take the second puff following exactly the same steps you used for the first puff. Press the canister one time for each puff of medicine.
  
  
  • When you are finished, wipe off the mouthpiece and replace the cap.
  
  


• Your doctor may want you to use a spacer device or holding chamber with the inhaler. A spacer helps get the medicine into the lungs and reduces the amount of medicine that stays in your mouth and throat.
  
  • To use a spacer device with the inhaler:
    
    • Attach the spacer to the inhaler according to the manufacturer's directions. There are different types of spacers available, but the method of breathing remains the same with most spacers.
    
    
    • Gently shake the inhaler and spacer three or four times.
    
    
    • Hold the mouthpiece of the spacer away from your mouth and breathe out slowly to the end of a normal breath.
    
    
    • Place the mouthpiece into your mouth between your teeth and over your tongue with your lips closed around it.
    
    
    • Press the top of the canister once to release one puff of medicine into the spacer. Within 1 or 2 seconds, start to breathe in slowly and deeply through your mouth for 5 to 10 seconds. Count the seconds while inhaling. Do not breathe in through your nose.
    
    
    • Hold your breath as long as you can up to 10 seconds.
    
    
    • Take the mouthpiece away from your mouth and breathe out slowly.
    
    
    • If your doctor has told you to take more than one puff of medicine at each dose, gently shake the inhaler and spacer again and take the next puff, following exactly the same steps you used for the first puff. Do not put more than one puff of medicine into the spacer at a time.
    
    
    • When you are finished, remove the spacer device from the inhaler and replace the cap.
    
    
  
  


• The mouthpiece has a dose indicator window that shows how much medicine is left. When the dose indicator window displays "40" or changes from green to red color background, this means that you need to refill your prescription or ask your doctor if you need another prescription of ipratropium.


• Clean the inhaler, mouthpiece, and spacer at least once a week.
  
  • To clean the inhaler:
    
    • Remove the canister from the inhaler and set aside.
    
    
    • Wash the mouthpiece, cap, and the spacer with warm, soapy water. Then, rinse well with warm, running water.
    
    
    • Shake off the excess water and let the inhaler parts air dry completely before putting the inhaler back together.
    
    
  
  

For patients using the inhalation solution:

• Use ipratropium only in a power-operated nebulizer with an adequate flow rate and equipped with a face mask or mouthpiece. Your doctor will tell you which nebulizer to use. Make sure you understand exactly how to use it. If you have any questions about this, check with your doctor.


• To prepare the medicine for use in the nebulizer:
  
  • If you are using the single-dose vial of ipratropium:
    
    • Break away one vial by pulling it firmly from the strip.
    
    
    • Twist off the top to open the vial. Use the contents of the vial as soon as possible after opening it.
    
    
    • Squeeze the contents of the vial into the cup of the nebulizer. If your doctor has told you to use less than a full vial of solution, use a syringe to withdraw the correct amount of solution from the vial and add it to the nebulizer cup. Be sure to throw away the syringe after one use.
    
    
  
  
  • If you are using the multiple-dose bottle of ipratropium:
    
    • Use a syringe to withdraw the correct amount of solution from the bottle and add it to the nebulizer cup. Do not use the same syringe more than once.
    
    
  
  


• If you have been told to dilute the ipratropium inhalation solution in the nebulizer cup with the sodium chloride solution provided, use a new syringe to add the sodium chloride solution to the cup as directed by your doctor.


• If your doctor told you to use another inhalation solution with the ipratropium inhalation solution, add that solution also to the nebulizer cup.


• To use the nebulizer:
  
  • Gently shake the nebulizer cup to mix the solutions well.
  
  
  • Connect the nebulizer tube to the air or oxygen pump and begin the treatment. Adjust the mask, if you are using one, to prevent mist from getting into your eyes.
  
  
  • Use the method of breathing your doctor told you to use to take the treatment. One way is to breathe slowly and deeply through the mask or mouthpiece. Another way is to breathe in and out normally with the mouthpiece in your mouth, taking a deep breath every 1 or 2 minutes. Continue to breathe in the medicine as instructed until no more mist is formed in the nebulizer cup or until you hear a sputtering (spitting or popping) sound.
  
  
  • When you have finished, replace the caps on the solutions. Store the bottles of solution in the refrigerator until the next treatment.
  
  
  • Clean the nebulizer according to the manufacturer's directions.
  
  

Use only the brand of ipratropium that your doctor prescribed. Different brands may not work the same way.

Dosing

The dose of ipratropium will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of ipratropium. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For asthma:
  
  • For inhalation aerosol dosage form (used with an inhaler):
    
    • Adults and children 12 years of age and older—1 to 4 puffs four times a day, at regularly spaced times, as needed.
    
    
    • Children up to 12 years of age—1 or 2 puffs three or four times a day, at regularly spaced times, as needed.
    
    
  
  
  • For inhalation solution dosage form (used with a nebulizer):
    
    • Adults and children 12 years of age and older—500 mcg used in a nebulizer three or four times a day, every 6 to 8 hours, as needed.
    
    
    • Children 5 to 12 years of age—125 to 250 mcg used in a nebulizer three or four times a day, every 4 to 6 hours as needed.
    
    
    • Children up to 5 years of age—Use and dose must be determined by your doctor.
    
    
  
  


• For symptoms of chronic obstructive pulmonary disease (COPD):
  
  • For inhalation aerosol dosage form (used with an inhaler):
    
    • Adult—At first, 2 puffs four times a day and as needed. Do not use more than 12 puffs in any 24-hour period.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For inhalation solution dosage form (used with a nebulizer):
    
    • Adults and children 12 years of age and older—250 to 500 mcg used in a nebulizer three or four times a day, every 6 to 8 hours.
    
    
    • Children up to 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of ipratropium, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep ipratropium inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using ipratropium

It is very important that your doctor check your progress closely while you are using ipratropium to see if it is working properly and to help reduce any unwanted effects.

Check with your doctor at once if your symptoms do not improve within 30 minutes after using a dose of ipratropium or if your condition gets worse.

For patients using ipratropium inhalation solution:

• If you are also using cromolyn inhalation solution, do not mix that solution with the ipratropium inhalation solution containing the preservative benzalkonium chloride for use in a nebulizer. To do so will cause the solution to become cloudy. However, if your condition requires you to use cromolyn inhalation solution with ipratropium inhalation solution, it may be mixed with ipratropium inhalation solution that is preservative-free.

ipratropium may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop using ipratropium and call your doctor right away if you have a rash; itching; hives; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, mouth, or throat while you are using ipratropium.

ipratropium may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Stop using ipratropium and check with your doctor right away if you have coughing, difficulty breathing, shortness of breath, or wheezing after using ipratropium.

ipratropium may cause dizziness, blurred vision, or trouble in seeing clearly. Make sure you know how you react to ipratropium before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to see well.

Take all of your COPD medicines as your doctor ordered. If you use any type of corticosteroid medicine to control your breathing, keep using it as ordered by your doctor. This includes corticosteroid medicines that are taken by mouth or inhaled (such as prednisone, Azmacort®, or Flovent®). If any of your COPD medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

ipratropium Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bladder pain


• bloody or cloudy urine


• cough producing mucus


• difficult, burning, or painful urination


• difficulty with breathing


• frequent urge to urinate


• lower back or side pain


• shortness of breath


• tightness in the chest


• wheezing

Less common

• Body aches or pain


• chills


• cough


• ear congestion


• fever


• headache


• loss of voice


• runny nose


• sneezing


• sore throat


• unusual tiredness or weakness

Rare

• Constipation (continuing) or lower abdominal pain or bloating


• fainting


• fast, pounding, or irregular heartbeat or pulse


• severe eye pain


• skin rash or hives


• swelling of the face, lips, or eyelids

Incidence not known

• Blindness


• blurred vision


• confusion


• decrease in the frequency of urination


• decrease in the urine volume


• decreased vision


• difficulty in passing urine (dribbling)


• difficulty with swallowing


• dizziness


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• hives or welts


• itching


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• nausea or vomiting


• noisy breathing


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• redness of the skin


• redness of the white part of the eyes or inside of the eyelids


• sweating


• tearing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Back pain


• dryness of the mouth


• unpleasant taste

Less common or rare

• Acid or sour stomach


• belching


• burning eyes


• diarrhea


• general feeling of discomfort or illness


• heartburn


• indigestion


• joint pain


• loss of appetite


• muscle aches and pains


• nervousness


• pain or tenderness around the eyes and cheekbones


• shivering


• stomach discomfort, upset, or pain


• trembling


• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More ipratropium Inhalation, oral/nebulization resources

• Ipratropium Inhalation, oral/nebulization Use in Pregnancy & Breastfeeding
• Ipratropium Inhalation, oral/nebulization Drug Interactions
• Ipratropium Inhalation, oral/nebulization Support Group
• 5 Reviews for Ipratropium Inhalation,/nebulization - Add your own review/rating

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Paracet

Paracet may be available in the countries listed below.

Ingredient matches for Paracet

Paracetamol

Paracetamol is reported as an ingredient of Paracet in the following countries:

• Norway


• Serbia


• South Africa


• Turkey

International Drug Name Search

pramipexole

pram-i-PEX-ole

Commonly used brand name(s)

In the U.S.

• Mirapex


• Mirapex ER

Available Dosage Forms:

• Tablet, Extended Release


• Tablet

Therapeutic Class: Antiparkinsonian

Pharmacologic Class: Dopamine Agonist

Uses For pramipexole

Pramipexole is used to treat Parkinson's disease. It may be used alone, or in combination with levodopa or other medicines to treat this disease.

Pramipexole is also used to treat a condition called Restless Legs Syndrome (RLS). RLS is a neurologic disorder that affects sensation and movement in the legs and causes the legs to feel uncomfortable. This results in an irresistible feeling of wanting to move your legs to make them comfortable. .

pramipexole is available only with your doctor's prescription.

Before Using pramipexole

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pramipexole, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to pramipexole or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of pramipexole in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pramipexole in the elderly. However, elderly patients are more likely to develop hallucinations (seeing, hearing, or feeling things that are not there), which may require caution in patients receiving pramipexole.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking pramipexole, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using pramipexole with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cimetidine


• Kava

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of pramipexole. Make sure you tell your doctor if you have any other medical problems, especially:

• Dyskinesia (trouble controlling your muscles) or


• Hallucinations or


• Hypotension (low blood pressure) or


• Postural hypotension (dizziness, lightheadedness, or fainting, especially when getting up from a lying or sitting position)—Use with caution. Pramipexole may make these conditions worse.

• Kidney problems—Higher blood levels of pramipexole may result, and cause an increase in side effects.

• Sleep disorders or


• Sleepiness, history of in the past—May cause side effects to be worse.

Proper Use of pramipexole

Take pramipexole every day exactly as directed by your doctor in order to improve your condition as much as possible. Do not take more or less of it, and do not take it more or less often than your doctor ordered.

Read the Patient Information leaflet before you take pramipexole and each time you get your prescription refilled. Ask your doctor if you have any questions.

You may take pramipexole with or without food. Taking pramipexole with food may reduce nausea.

Swallow the extended-release tablets whole. Do not break, crush, or chew it.

Dosing

The dose of pramipexole will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of pramipexole. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release tablet):
  
  • Adults—At first, 0.375 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 4.5 mg per day.
  
  
  • Children—Use and dose must be determined by your doctor.
  
  


• For oral dosage form (tablets):
  
  • For Parkinson's disease:
    
    • Adults—At first, 0.125 milligram (mg) three times a day. Your doctor will gradually increase your dose as needed and tolerated. However, the dose is usually not more than 4.5 mg per day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For Restless Legs Syndrome:
    
    • Adults—At first, 0.125 milligram (mg) once a day 2 to 3 hours before bedtime. Your doctor will gradually increase your dose as needed and tolerated. However, the dose usually is not more than 0.5 mg a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of pramipexole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using pramipexole

It is very important that your doctor check your progress at regular visits. This is to allow changes in your dose and to check for any unwanted effects.

Do not stop taking pramipexole without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely.

People taking pramipexole have reported falling asleep without warning during activities of daily living, including driving, which sometimes resulted in accidents. This may happen as late as one year after taking the medicine. Therefore, make sure you know how you react to pramipexole before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well.

pramipexole will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates or medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking pramipexole.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. These symptoms are more likely to occur when you begin taking pramipexole, or when the dose is increased. Getting up slowly may help. If you should have this problem, check with your doctor.

Hallucinations (seeing, hearing, or feeling things that are not there) may occur in some patients. This is more common with elderly patients. If you have hallucinations, check with your doctor.

Check with your doctor right away if you have dark-colored urine, fever, muscle cramps or spasms, muscle pain or stiffness, or unusual tiredness or weakness. These may be symptoms of a condition called rhabdomyolysis.

It is important that your doctor check your skin for melanoma (tumor) regularly if you have Parkinson's disease.

Some people who have used pramipexole had unusual changes in their behavior, such as having problems with gambling, increased sex drive, or compulsive eating. Talk with your doctor if this is a concern for you.

pramipexole Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Dizziness, lightheadedness, or fainting, especially when standing up


• drowsiness


• hallucinations (seeing, hearing, or feeling things that are not there)


• nausea


• trouble with sleeping


• twitching, twisting, or other unusual body movements


• unusual tiredness or weakness

Less common

• Confusion


• cough


• difficulty with swallowing


• double vision or other changes in vision


• falling asleep without warning


• fearfulness, suspiciousness, or other mental changes


• fever


• frequent urination


• memory loss


• muscle or joint pain


• muscle weakness


• restlessness or need to keep moving


• shortness of breath


• swelling of the body


• tightness in the chest


• troubled breathing


• wheezing


• writhing, twisting, or other unusual body movements

Rare

• Abnormal thinking


• anxiety


• bloody or cloudy urine


• chest pain


• difficult, burning, or painful urination


• dizziness


• frequent urge to urinate


• loss of bladder control


• mood or mental changes


• swelling of the arms or legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation


• dryness of the mouth


• headache


• heartburn, indigestion, or acid stomach

Less common

• Abnormal dreams


• decreased sexual drive or ability


• general feeling of discomfort or illness


• increased cough


• increased sweating


• itching


• joint pain


• loss of appetite


• runny nose


• skin problems, such as rash or itching


• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: pramipexole side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More pramipexole resources

• Pramipexole Side Effects (in more detail)
• Pramipexole Use in Pregnancy & Breastfeeding
• Drug Images
• Pramipexole Drug Interactions
• Pramipexole Support Group
• 46 Reviews for Pramipexole - Add your own review/rating

• Pramipexole MedFacts Consumer Leaflet (Wolters Kluwer)


• Pramipexole Prescribing Information (FDA)


• Mirapex Prescribing Information (FDA)


• Mirapex Monograph (AHFS DI)


• Mirapex Consumer Overview


• Mirapex ER Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Mirapex ER Prescribing Information (FDA)

Compare pramipexole with other medications

• Parkinson's Disease
• Periodic Limb Movement Disorder
• Restless Legs Syndrome
• Tardive Dyskinesia

Permethrin 5% w / w Cream (Sandoz Limited)

1. Name Of The Medicinal Product

Permethrin 5% w/w Cream

2. Qualitative And Quantitative Composition

Permethrin 5% w/w (cis:trans isomer 25:75)

For excipients, see 6.1.

3. Pharmaceutical Form

Cream.

4. Clinical Particulars

4.1 Therapeutic Indications

Permethrin 5% Cream is indicated for the treatment of scabies.

4.2 Posology And Method Of Administration

Permethrin 5% Cream is suitable for adults, children of 2 months of age and above, and the elderly.

Permethrin 5% Cream is for external use only and should not be applied to broken skin, mucous membranes or near the eyes.

Permethrin 5% Cream should be applied to skin which is clean dry and cool. It should not be used immediately after a hot bath.

Children under 2 years should only be treated under medical supervision.

Older children should be supervised when applying the cream.

Permethrin 5% Cream is intended for a single application over the whole body. In view of the great variability in body area and skin types, precise dosage recommendations are not possible.

In cases where the head, neck, scalp and ears are treated (see below), the dosage may be increased to ensure total body coverage.

Adults, the elderly & children over 12 years	Normally, up to one tube (30g). A few adults may need to use an additional tube for full body coverage but should not use more than 2 tubes (60g in total) at each application.
Children 6 to 12 years	Up to half a tube (15g).
Children 1 to 5 years	Up to a quarter of a tube (7.5g).
Children 2 months to 1 year	Up to an eighth of a tube (3.75g).

Adults & children over 2 years:

Apply the cream over the whole body but NOT the head and face. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts and buttocks.

The elderly:

Apply the cream over the whole body INCLUDING the neck, face, ears and scalp. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts and buttocks. Avoid the area close to the eyes.

Children under 2 years:

Apply the cream over the whole body INCLUDING the neck, face, ears and scalp. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, palms of hands and soles of feet, external genitals and buttocks. Avoid the area around the mouth where the cream could be licked off and the area around the eyes.

The cream should be left on for at least 8 hours.

Reapply the cream to the hands if they are washed within 8 hours of treatment.

The whole body should be washed thoroughly 8-12 hours after application.

Approximately 90% of individuals are cured after a single application. If there are no signs of the original lesions healing or if new lesions have appeared, a second application can be made not less than 7 days after the first application.

4.3 Contraindications

Hypersensitivity to permethrin, to other pyrethroids or pyrethrins, or to any other ingredients of the cream.

4.4 Special Warnings And Precautions For Use

Permethrin 5% Cream should be kept out of the reach of children.

Permethrin 5% Cream is for external use only. Nursing staff who routinely apply Permethrin 5% Cream may wish to wear gloves to avoid any possible irritation to the hand.

Avoid contact with the eyes. The cream can cause eye irritation. If you do get cream in your eyes, rinse with water immediately.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

The treatment of eczematous-like reactions with corticosteroids should be withheld prior to treatment with Permethrin 5% Cream, as there is a risk of exacerbating the scabies infestation by reducing the immune response to the mite. The likelihood of interactions between the two treatments leading to potentiated adverse reactions or reduced efficacy is, however small.

4.6 Pregnancy And Lactation

The limited data available on the use of Permethrin 5% Cream show no indication of any risk to the foetus. The amount of permethrin absorbed systemically following a whole body application is extremely low. However, some permethrin may pass the placental barrier. The negative mutagenicity tests and the very low mammalian toxicity suggest that there is minimal risk to the foetus following treatment with permethrin.

It has been shown that very low concentrations of permethrin are excreted in milk following oral administration of permethrin in cattle. It is not known whether permethrin is excreted in human breast milk. However, it is unlikely that the concentrations of permethrin in the milk will present any risk to the neonate/infant as only extremely small amounts of permethrin are absorbed systemically and in theory only a very small percentage of this will pass into the breast milk.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

Occasional reports of

• Burning or stinging sensation which passes quickly. This is usually mild and occurs more frequently in patients with severe scabies.

• Transient signs and symptoms of skin irritation including rash or itching, erythema, oedema and eczema.

These are generally considered to be part of the natural history of scabies. Itching may persist for up to 4 weeks after treatment. This is an allergic reaction to the dead scabies mites. It is normal and is not a sign that treatment has failed.

4.9 Overdose

There are no reports of overdosage of Permethrin 5% Cream.

Excessive application to the skin might result in local adverse reactions. Application of a full tube (30g) of cream to a 2-month old would result in a dose of approximately 350mg/kg bodyweight. Even if completely absorbed, this dose would be unlikely produce overt signs of systemic toxicity.

In the event of accidental ingestion by a child, gastric lavage should be considered if within 2 hours of ingestion.

Treatment of hypersensitivity reactions should be symptomatic.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

The principal physiological action in susceptible parasites exposed to permethrin is induction of electrochemical abnormalities across the membranes of excitable cells, leading to sensory hyper-excitability, inco-ordination and prostration.

5.2 Pharmacokinetic Properties

Permethrin is rapidly metabolised in mammals by ester hydrolysis to inactive metabolites which are excreted principally via the kidneys. The principal metabolites are detectable in the urine within 7 hours of whole body application of the cream to healthy volunteers or scabies patients. The highest levels of excretion are detectable within 48 hours but very low levels of metabolite are still detectable in the urine of some individuals 28 days after treatment. The overall pattern of excretion indicates that approximately 0.5% of applied permethrin is absorbed in the first 48 hours.

5.3 Preclinical Safety Data

In vitro and in vivo genetic toxicity studies were all negative, revealing no potential for permethrin to induce mutagenic changes.

Long-term studies in rats revealed no evidence of oncogenicity. Similar studies in mice have shown species specific increases in pulmonary adenomas, a common benign tumour of mice of high spontaneous background incidence. In one of these studies, there was an increased incidence of benign liver adenomas and of pulmonary alveolar cell carcinomas only in female mice when permethrin was given in their food for two years (approximately 750 mg/kg bodyweight/day). These findings are not considered to indicate a significant oncogenic potential for permethrin in humans.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Cetylstearyl alcohol

Paraffin, hard

Cetomacrogol 1000

Isopropylmyristate

Benzyl alcohol

Purified water

6.2 Incompatibilities

None known

6.3 Shelf Life

24 months

6.4 Special Precautions For Storage

Do not store above 25°C. Do not freeze.

6.5 Nature And Contents Of Container

Aluminium tube with polypropylene cap. Contains 30g of cream.

6.6 Special Precautions For Disposal And Other Handling

None

Administrative Data

7. Marketing Authorisation Holder

Sandoz Ltd

Woolmer Way

Bordon

Hampshire

GU35 9QE

8. Marketing Authorisation Number(S)

PL 4416/0456

9. Date Of First Authorisation/Renewal Of The Authorisation

9 September 2003

10. Date Of Revision Of The Text

9 September 2003

Ventisal

Ventisal may be available in the countries listed below.

Ingredient matches for Ventisal

Salbutamol

Salbutamol sulfate (a derivative of Salbutamol) is reported as an ingredient of Ventisal in the following countries:

• Bangladesh

International Drug Name Search

Insulin Lispro Vials

Pronunciation: IN-su-lin LIS-pro
Generic Name: Insulin Lispro
Brand Name: Humalog

Insulin Lispro Vials are used for:

Treating diabetes mellitus. Insulin Lispro Vials are usually used with a longer-acting insulin or insulin pump therapy. In some patients, it may be used with a sulfonylurea antidiabetic instead of a longer-acting insulin.

Insulin Lispro Vials are a fast-acting form of the hormone insulin. It works by helping your body to use sugar properly. This lowers the amount of glucose in the blood, which helps to treat diabetes.

Do NOT use Insulin Lispro Vials if:

• you are allergic to any ingredient in Insulin Lispro Vials


• you are having an episode of low blood sugar

Contact your doctor or health care provider right away if any of these apply to you.

Before using Insulin Lispro Vials:

Some medical conditions may interact with Insulin Lispro Vials. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you drink alcoholic beverages or smoke


• if you have kidney or liver problems; nerve problems; adrenal, pituitary or thyroid problems; or diabetic ketoacidosis


• if you use 3 or more insulin injections per day


• if you are fasting, have high blood sodium levels, or are on a low salt diet

Some MEDICINES MAY INTERACT with Insulin Lispro Vials. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), clonidine, guanethidine, lithium, or reserpine because they may increase the risk of high or low blood sugar or may hide the signs and symptoms of low blood sugar, if it occurs


• Angiotensin-converting (ACE) inhibitors (eg, enalapril), disopyramide, fenfluramine, fibrates (eg, clofibrate, gemfibrozil), fluoxetine, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), oral medicine for diabetes (eg, glipizide, metformin, nateglinide), pentamidine, propoxyphene, salicylates (eg, aspirin), somatostatin analogs (eg, octreotide), or sulfonamide antibiotics (eg, sulfamethoxazole) because the risk of low blood sugar may be increased


• Corticosteroids (eg, prednisone), danazol, diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, chlorpromazine), progesterones (eg, medroxyprogesterone), somatropin, sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid hormones (eg, levothyroxine) because they may decrease Insulin Lispro Vials's effectiveness, resulting in high blood sugar

This may not be a complete list of all interactions that may occur. Ask your health care provider if Insulin Lispro Vials may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Insulin Lispro Vials:

Use Insulin Lispro Vials as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Insulin Lispro Vials. Talk to your pharmacist if you have questions about this information.


• Use Insulin Lispro Vials within 15 minutes before or immediately after a meal, unless directed otherwise by your doctor.


• If you will be using Insulin Lispro Vials at home, a health care provider will teach you how to use it. Be sure you understand how to use Insulin Lispro Vials. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• You may use Insulin Lispro Vials in an insulin pump if you are directed to do so by your doctor. If you are using an insulin pump, do NOT dilute Insulin Lispro Vials or mix it together with any other type of insulin.


• Insulin Lispro Vials should be clear and colorless. Do not use Insulin Lispro Vials if it contains particles, is cloudy and discolored, or if the vial is cracked or damaged.


• If you are mixing Insulin Lispro Vials with another insulin, draw Insulin Lispro Vials into the syringe first. Inject the dose immediately after mixing, as directed by your doctor.


• Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into a vein or muscle.


• Injection sites within an injection area (abdomen, thigh, upper arm) must be rotated from one injection to the next.


• Be sure you have purchased the correct insulin. Insulin comes in a variety of containers, including vials, cartridges, and pens. Make sure that you understand how to properly measure and prepare your dose. If you have any questions about measuring and preparing your dose, contact your doctor or pharmacist for information.


• Insulin Lispro Vials begins lowering blood sugar within minutes after an injection. The peak effect occurs within 30 to 90 minutes after a dose. The effect lasts for up to 2 to 5 hours.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.


• It is very important to follow your insulin regimen exactly. Do NOT miss any doses. Ask your doctor for specific instructions to follow in case you should ever miss a dose of insulin.

Ask your health care provider any questions you may have about how to use Insulin Lispro Vials.

Important safety information:

• Insulin Lispro Vials may cause dizziness, drowsiness, or changes in vision. These effects may be worse if you take it with alcohol or certain medicines. Use Insulin Lispro Vials with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol without discussing it with your doctor. Drinking alcohol may increase the risk of developing high or low blood sugar.


• Do not use more than the recommended dose, use Insulin Lispro Vials more often than prescribed, or change the type or dose of insulin you are using without checking with your doctor.


• Any change of insulin should be made cautiously and only under medical supervision. Changes in purity, strength, brand (manufacturer), type (regular, NPH, lente), species (beef, pork, beef-pork, human), and/or method of manufacture may require a change in dose.


• Illness, especially with nausea and vomiting, may cause your insulin requirements to change. Even if you are not eating, you will still require insulin. You and your doctor should establish a sick day plan to use in case of illness. When you are sick, test your blood/urine frequently and call your doctor as instructed.


• Tell your doctor or dentist that you take Insulin Lispro Vials before you receive any medical or dental care, emergency care, or surgery.


• If you will be traveling across time zones, consult your doctor concerning adjustments in your insulin schedule.


• Carry an ID card at all times that says you have diabetes.


• An insulin reaction resulting from low blood sugar levels (hypoglycemia) may occur if you take too much insulin, skip a meal, or exercise too much. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.


• Developing a fever or infection, eating significantly more than prescribed, or missing your dose of insulin may cause high blood sugar (hyperglycemia). High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If not treated, loss of consciousness, coma, or death may occur. If these symptoms occur, tell your doctor right away.


• Check with your doctor if you notice a depression in the skin or skin thickening at the injection site. You may need to change your injection technique.


• Proper diet, regular exercise, and regular testing of blood sugar are important for best results when using Insulin Lispro Vials.


• Lab tests, including fasting blood glucose levels and hemoglobin A_1c levels, may be performed while you use Insulin Lispro Vials. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Insulin Lispro Vials with caution in the ELDERLY; if low blood sugar occurs, it may be more difficult to recognize in these patients.


• Insulin Lispro Vials should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Insulin Lispro Vials while you are pregnant. It is not known if Insulin Lispro Vials are found in breast milk. If you are or will be breast-feeding while you use Insulin Lispro Vials, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Insulin Lispro Vials:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness, swelling, itching, or mild pain at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing; muscle pain); changes in vision; chills; confusion; dizziness; drowsiness; fainting; fast or irregular heartbeat; headache; loss of consciousness; mood changes; seizures; slurred speech; swelling; tremor; trouble breathing; trouble concentrating; unusual hunger; unusual sweating; weakness; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center or emergency room immediately. Symptoms may include chills; dizziness; drowsiness; fainting; fast or irregular heartbeat; headache; loss of consciousness; nervousness; seizures; shakiness; sweating; tremor; vision changes; weakness.

Proper storage of Insulin Lispro Vials:

Store new (unopened) vials in a refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze Insulin Lispro Vials. Store used (open) vials either in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), or at room temperature, below 86 degrees F (30 degrees C). Store away from heat and light. If Insulin Lispro Vials has been frozen or overheated, throw it away. Throw away unrefrigerated or opened vials after 28 days, even if they still contain medicine.

Avoid temperatures above 98.6 degrees F (37 degrees C). Do not leave Insulin Lispro Vials in a car on a warm or sunny day. Do not use Insulin Lispro Vials after the expiration date stamped on the label. Keep Insulin Lispro Vials, as well as syringes and needles, out of the reach of children and away from pets. If you are using Insulin Lispro Vials in an insulin pump, or if Insulin Lispro Vials has been mixed with other medicines or diluted, you may need to store it differently. Ask your doctor, pharmacist, or other health care provider how to store Insulin Lispro Vials.

General information:

• If you have any questions about Insulin Lispro Vials, please talk with your doctor, pharmacist, or other health care provider.


• Insulin Lispro Vials are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Insulin Lispro Vials. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Insulin Lispro resources

• Insulin Lispro Use in Pregnancy & Breastfeeding
• Insulin Lispro Drug Interactions
• Insulin Lispro Support Group
• 4 Reviews for Insulin Lispro - Add your own review/rating

Compare Insulin Lispro with other medications

• Diabetes, Type 1
• Diabetes, Type 2

Omig

Omig may be available in the countries listed below.

Ingredient matches for Omig

Omeprazole

Omeprazole is reported as an ingredient of Omig in the following countries:

• India

International Drug Name Search

Rifadin

Rifadin is a brand name of rifampin, approved by the FDA in the following formulation(s):

RIFADIN (rifampin - capsule; oral)

• 
  Manufacturer: SANOFI AVENTIS US
  
  Approved Prior to Jan 1, 1982
  
  Strength(s): 300MG ^[RLD][AB]

RIFADIN (rifampin - injectable; injection)

• 
  Manufacturer: SANOFI AVENTIS US
  
  Approval date: May 25, 1989
  
  Strength(s): 600MG/VIAL ^[RLD][AP]

Has a generic version of Rifadin been approved?

Yes. The following products are equivalent to Rifadin:

rifampin capsule; oral

• 
  Manufacturer: LANNETT
  
  Approval date: March 28, 2008
  
  Strength(s): 300MG ^[AB]


• 
  Manufacturer: SANDOZ
  
  Approval date: May 28, 1997
  
  Strength(s): 300MG ^[AB]


• 
  Manufacturer: VERSAPHARM
  
  Approval date: March 14, 2001
  
  Strength(s): 300MG ^[AB]

rifampin injectable; injection

• 
  Manufacturer: BEDFORD
  
  Approval date: October 29, 1999
  
  Strength(s): 600MG/VIAL ^[AP]


• 
  Manufacturer: PFIZER
  
  Approval date: May 22, 2008
  
  Strength(s): 600MG/VIAL ^[AP]


• 
  Manufacturer: VERSAPHARM INC
  
  Approval date: September 21, 2010
  
  Strength(s): 600MG/VIAL ^[AP]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Rifadin. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.

Related Patents

There are no current U.S. patents associated with Rifadin.

See also...

• Rifadin Consumer Information (Wolters Kluwer)
• Rifadin Consumer Information (Cerner Multum)
• Rifadin Advanced Consumer Information (Micromedex)
• Rifampin Consumer Information (Wolters Kluwer)
• Rifampin Capsules Consumer Information (Wolters Kluwer)
• Rifampin Consumer Information (Cerner Multum)
• Rifampin Intravenous Advanced Consumer Information (Micromedex)
• Rifampin Oral, Intravenous Advanced Consumer Information (Micromedex)
• Rifampin AHFS DI Monographs (ASHP)

Adofen Semanal

Adofen Semanal may be available in the countries listed below.

Ingredient matches for Adofen Semanal

Fluoxetine

Fluoxetine hydrochloride (a derivative of Fluoxetine) is reported as an ingredient of Adofen Semanal in the following countries:

• Spain

International Drug Name Search

Omeben

Omeben may be available in the countries listed below.

Ingredient matches for Omeben

Omeprazole

Omeprazole is reported as an ingredient of Omeben in the following countries:

• Bangladesh

International Drug Name Search

Dextromethorphan Chewable Tablets

Pronunciation: DEX-troe-meth-OR-fan
Generic Name: Dextromethorphan
Brand Name: Triaminic Softchews Cough

Dextromethorphan Chewable Tablets are used for:

Temporarily relieving cough due to the common cold, upper respiratory tract infections, sinus inflammation, sore throat, or bronchitis.

Dextromethorphan Chewable Tablets are a cough suppressant. It works by loosening mucus and lung secretions in the chest and making coughs more productive.

Do NOT use Dextromethorphan Chewable Tablets if:

• you are allergic to any ingredient in Dextromethorphan Chewable Tablets


• you are taking or have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dextromethorphan Chewable Tablets:

Some medical conditions may interact with Dextromethorphan Chewable Tablets. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have chronic cough, chronic bronchitis or any breathing problems, such as asthma, emphysema, chronic obstructive pulmonary disease (COPD), or if cough occurs with a large amount of mucus

Some MEDICINES MAY INTERACT with Dextromethorphan Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Furazolidone or MAO inhibitors (eg, phenelzine) because the risk of toxic side effects may be increased by Dextromethorphan Chewable Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dextromethorphan Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dextromethorphan Chewable Tablets:

Use Dextromethorphan Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dextromethorphan Chewable Tablets may be taken with or without food. Take with food if stomach upset occurs.


• Chew thoroughly before swallowing.


• If you miss a dose of Dextromethorphan Chewable Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dextromethorphan Chewable Tablets.

Important safety information:

• Dextromethorphan Chewable Tablets may cause drowsiness, dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dextromethorphan Chewable Tablets. Using Dextromethorphan Chewable Tablets alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.


• If your cough lasts for more than 1 week or comes back, or if you also have a fever, rash, or persistent headache, contact your health care provider. A persistent cough could be a sign of a serious condition.


• Dextromethorphan Chewable Tablets contains dextromethorphan. Before you being taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains dextromethorphan. If it does or if you are not sure, contact your health care provider or pharmacist.


• Phenylketonuria patients - Dextromethorphan Chewable Tablets contains phenylalanine.


• Dextromethorphan Chewable Tablets are not recommended for use in CHILDREN younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Dextromethorphan Chewable Tablets during pregnancy. It is unknown if Dextromethorphan Chewable Tablets are excreted in breast milk. Do not breast-feed while taking Dextromethorphan Chewable Tablets.

Possible side effects of Dextromethorphan Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dextromethorphan side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; excitement; hallucinations; slowed breathing.

Proper storage of Dextromethorphan Chewable Tablets:

Store Dextromethorphan Chewable Tablets between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Do not store in the bathroom. Keep Dextromethorphan Chewable Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Dextromethorphan Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Dextromethorphan Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dextromethorphan Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dextromethorphan resources

• Dextromethorphan Side Effects (in more detail)
• Dextromethorphan Dosage
• Dextromethorphan Use in Pregnancy & Breastfeeding
• Dextromethorphan Drug Interactions
• Dextromethorphan Support Group
• 8 Reviews for Dextromethorphan - Add your own review/rating

Compare Dextromethorphan with other medications

• Cough

Pracne

Pracne may be available in the countries listed below.

Ingredient matches for Pracne

Minocycline

Minocycline is reported as an ingredient of Pracne in the following countries:

• Chile

International Drug Name Search

Urapidil

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C02CA06

CAS registry number (Chemical Abstracts Service)

0034661-75-1

Chemical Formula

C20-H29-N5-O3

Molecular Weight

387

Therapeutic Category

Antihypertensive agent

Chemical Name

2,4(1H,3H)-Pyrimidinedione, 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-

Foreign Names

• Urapidilum (Latin)
• Urapidil (German)
• Urapidil (French)
• Urapidil (Spanish)

Generic Names

• Urapidil (OS: JAN, DCF, DCIT, BAN)
• B 66256 (IS: Byk Gulden)

Brand Names

• Ebrantil
  Altana, Bosnia & Herzegowina; Altana, Czech Republic; Altana, Hungary; Altana, Luxembourg; Altana, Poland; Kaken Seiyaku, Japan; Nycomed, Austria; Nycomed, Germany; Nycomed, Croatia (Hrvatska); Nycomed, Italy; Nycomed, Netherlands; Nycomed, Serbia; Nycomed, Slovenia; Nycomed, Slovakia; Sanwa Kagaku, Japan



• Eupressyl
  Nycomed, France



• Médiatensyl
  Nycomed, France



• Urapidil Carino
  Carinopharm, Germany



• Urapidil-Pharmore
  Pharmore, Germany



• Ebrantil
  Altana, Belgium; Altana, Czech Republic; Altana, Hungary; Altana, Luxembourg; Nycomed, Austria; Nycomed, China; Nycomed, Germany; Nycomed, Georgia; Nycomed, Croatia (Hrvatska); Nycomed, Slovakia; Nycomed Pharma, Switzerland



• Elgadil
  Nycomed, Spain



• Eupressyl
  Nycomed, France



• Hypotrit
  Ebewe, Austria

International Drug Name Search

Glossary

BAN	British Approved Name
DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Zyprexa IM

Zyprexa IM may be available in the countries listed below.

Ingredient matches for Zyprexa IM

Olanzapine

Olanzapine is reported as an ingredient of Zyprexa IM in the following countries:

• South Africa

International Drug Name Search

Tecnovorin

Tecnovorin may be available in the countries listed below.

Ingredient matches for Tecnovorin

Calcium Folinate

Calcium Folinate is reported as an ingredient of Tecnovorin in the following countries:

• Brazil


• Peru

International Drug Name Search

Ranitidin Actavis

Ranitidin-Actavis may be available in the countries listed below.

Ingredient matches for Ranitidin-Actavis

Ranitidine

Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Ranitidin-Actavis in the following countries:

• Germany


• Sweden

International Drug Name Search

Tevabone

Tevabone may be available in the countries listed below.

Ingredient matches for Tevabone

Alendronic Acid

Alendronic Acid sodium trihydrate (a derivative of Alendronic Acid) is reported as an ingredient of Tevabone in the following countries:

• Germany

Alfacalcidol

Alfacalcidol is reported as an ingredient of Tevabone in the following countries:

• Germany

International Drug Name Search

Ixabepilone

Pronunciation: IX-ab-EP-i-lone
Generic Name: Ixabepilone
Brand Name: Ixempra

Do not take Ixabepilone if you also take capecitabine and you have high liver enzyme levels. It may increase your risk of toxicity and death caused by low white blood cell levels. Tell your doctor before you use Ixabepilone if you have liver problems.

Ixabepilone is used for:

Treating breast cancer. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Ixabepilone is a microtubule inhibitor. It works by blocking cancer cell growth and reproduction.

Do NOT use Ixabepilone if:

• you are allergic to any ingredient in Ixabepilone or to products that contain Cremophor EL or castor oil


• you have low white blood cell or platelet levels


• you have high liver enzyme levels and you also take capecitabine


• you are taking certain cephalosporins (eg, cefotetan), disulfiram, or metronidazole

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ixabepilone:

Some medical conditions may interact with Ixabepilone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of heart problems (eg, irregular heartbeat, a heart attack), diabetes, liver problems (eg, high liver enzyme levels), nerve problems, or bone marrow problems


• if you have an infection or blood problems (eg, low white blood cell or platelet levels)

Some MEDICINES MAY INTERACT with Ixabepilone. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Certain cephalosporins (eg, cefotetan), disulfiram, furazolidone, metronidazole, or sulfonylureas (eg, glyburide) because a reaction, including flushing, headache, fast or irregular heartbeat, difficult or fast breathing, nausea, vomiting, or dizziness, may occur


• Azole antifungals (eg, fluconazole, ketoconazole, voriconazole), delavirdine, HIV protease inhibitors (eg, amprenavir, atazanavir, ritonavir), macrolide antibiotics (eg, clarithromycin, erythromycin), nefazodone, telithromycin, trazodone, or verapamil because they may increase the risk of Ixabepilone's side effects


• Barbiturates (eg, phenobarbital), carbamazepine, dexamethasone, efavirenz, hydantoins (eg, phenytoin), rifabutin, rifampin, or St. John's wort because they may decrease Ixabepilone's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ixabepilone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ixabepilone:

Use Ixabepilone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Ixabepilone. Talk to your pharmacist if you have questions about this information.


• Ixabepilone is usually given once every 3 weeks. It is given as an injection at your doctor's office, hospital, or clinic. Each treatment will take about 3 hours.


• You will receive other medicines about 1 hour before each treatment with Ixabepilone to decrease the chance of an allergic reaction. Discuss any questions with your doctor.


• If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.


• Do not eat grapefruit or drink grapefruit juice while you are using Ixabepilone.


• If you miss a dose of Ixabepilone, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Ixabepilone.

Important safety information:

• Ixabepilone may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ixabepilone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Ixabepilone has alcohol in it and may interact with other medicines (eg, certain cephalosporins, disulfiram, furazolidone, metronidazole, sulfonylureas). Alcohol in drinks or other medicines may increase the effects of Ixabepilone. Before you start any new medicine, check the label to see if it has alcohol in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Ixabepilone may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.


• Ixabepilone may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.


• Check with your doctor before you receive any vaccine while you are using Ixabepilone.


• Tell your doctor or dentist that you take Ixabepilone before you receive any medical or dental care, emergency care, or surgery.


• Women who are able to become pregnant should use an effective form of birth control (eg, condoms) while using Ixabepilone. Ask your doctor any questions you may have about effective birth control.


• Lab tests, including complete blood cell counts and liver function, may be performed while you use Ixabepilone. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Ixabepilone with caution in the ELDERLY; they may be more sensitive to its effects.


• Ixabepilone should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Ixabepilone has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ixabepilone while you are pregnant. It is not known if Ixabepilone is found in breast milk. Do not breast-feed while using Ixabepilone.

Possible side effects of Ixabepilone:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; fingernail or toenail changes; hair loss; headache; loss of appetite; mild fever; mild joint or muscle pain; mouth sores; nausea; stomach pain or upset; taste changes; tiredness or weakness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; flushing; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); chest pain or tightness; fainting; fast or irregular heartbeat; numbness, tingling, or burning of the hands or feet; pain, swelling, redness, or blistering at the injection site; redness, tenderness, or dryness of the palms of hands or soles of feet; severe or persistent dizziness; severe or persistent nausea, vomiting, or diarrhea; severe tiredness or weakness; shortness of breath; signs of an infection (eg, fever, chills, cough, sore throat, burning or painful urination); swelling of the arms, hands, legs, or feet; unusual bruising or bleeding; unusual weight gain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Ixabepilone side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fatigue; loss of appetite; muscle pain or aches; severe burning, numbness, or tingling of the arms, hands, legs, or feet; severe diarrhea, nausea, or stomach pain; swelling or soreness of the mouth or tongue.

Proper storage of Ixabepilone:

Ixabepilone is usually handled and stored by a health care provider. If you are using Ixabepilone at home, store Ixabepilone as directed by your pharmacist or health care provider. Keep Ixabepilone out of the reach of children and away from pets.

General information:

• If you have any questions about Ixabepilone, please talk with your doctor, pharmacist, or other health care provider.


• Ixabepilone is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ixabepilone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ixabepilone resources

• Ixabepilone Side Effects (in more detail)
• Ixabepilone Use in Pregnancy & Breastfeeding
• Ixabepilone Drug Interactions
• Ixabepilone Support Group
• 0 Reviews for Ixabepilone - Add your own review/rating

• Ixabepilone Professional Patient Advice (Wolters Kluwer)


• Ixabepilone Monograph (AHFS DI)


• ixabepilone Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information


• Ixempra Prescribing Information (FDA)


• Ixempra Consumer Overview

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